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Histamine acts as a neurotransmitter involved in the contractions of the intestinal muscles.[ref] People with food allergies and IBS had significantly higher levels of H1 and H2 receptors in their intestines.[ref] Histamine receptors in the brain: A 2026 study explored the role of histamine and histamine receptors in different regions of the brain

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Addresses loss of elasticity and discoloration.

I'll occasionally take it every once in a while, but in general, I just stopped taking it because whatever the positive effects might've been, if I had taken it more consistently, the effects in depleting rapid eye movement sleep were just something I didn't want and don't want