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Oxidative stress caused by the microenvironment in endometriosis and its effects on the quality of oocytes, sperm, and embryos As discussed above, the data from the literature demonstrate lower implantation rates, lower pregnancy rates, and higher miscarriages rates in IVF patients with endometriosis

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Abbreviations AAS: Atomic absorption spectroscopy AD: Alzheimers disease ALS: Amyotrophic lateral sclerosis Atox1, CCS, HAH1, COX17: Copper chaperones ATP7A, ATP7B, Cu-ATPases: Copper-transporting P-type ATPases A: Amyloid beta CNS: Central nervous system CopC: Bacterial peripasmic copper binding proteins COX, mitochondrial complex IV: Cytochrome c oxidase (EC 1.9.3.1) CP: Choroid plexus Ctr1, Ctr2: Copper(I) transporters CTZ: cuprizone (bis-cyclohexanoneoxalyl-dihydrazone) Cu, Zn-SOD1: Copper, zinc superoxide dismutase CuAO: Copper aminooxidase CWD: Chronic wasting disease DMT1: Divalent metal transporter D-pen: D -penicillamine EM: Electron microscopy FAAS: Flameless atomic absorption spectroscopy GABA: Gamma-aminobutyric acid GHK: SPARC fragment Gly-His-Lys GSH: Gluthation (gamma-L-glutamyl-L-cysteinylglycine) GSSG:: Gluthation disulfide HC: Huntingtons chorea Htt: Huntingtin protein ICC: Indian childhood cirrhosis ICP-AES: Inductively coupled plasma - atomic emission spectrometry IPs: Inositol phosphates Kir4.1: Inwardly rectifying K + ion channel 4.1

Dumay J, Moranais M