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Groups 6 and 7 (HML1&HML2) received HML at doses that corresponded to 1/40 and 1/20 of the LD 50 , respectively (75 and 150 mg active ingredient/kg bwt, that equivalent to a human dose of 12- and 24 mg/kg bwt)

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Although the exact mechanisms are unknown, there are some variants that have been associated with a higher risk of getting Graves, such as DRB1*03 (in Whites and Blacks) and DPB1 (in Asians) [28]