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As for claims that the supplements support hair and nail health, the research is, well, brittle

Until commercially available synthetic PCB or PCB-enriched Spirulina extracts are available, consuming entire Spirulina is the most practical and least expensive approach to administer PCBs (Al-Qahtani and Binobead 2019)

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118,119 Although it is evident that antibodies against transacylation protein adducts may be involved in liver injury, the role of acyl glucuronides in liver injury remains controversial as acylation adducts could be formed through other pathways (e.g., Coenzyme A pathway)