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& Romano, R

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doi:10.3390/jox15010001 Moustakli E, Potiris A, Grigoriadis T, et al

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Nevertheless, DFOs clinical applicability is constrained by poor BBB penetration and non-oral administration route, prompting the development of modified delivery systems(e.g., DFO-gold nanoparticle conjugates, NCT05022472) currently under preclinical optimization

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In some embodiments, the otic formulation or composition comprises about 0.01% to about 1% by weight of the poloxamer

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