This susceptibility is compounded by impaired redox homeostasis and multiple pathogenic factors: i) dysfunctional protein clearance mechanisms involving PTEN-induced kinase 1 (PINK1), Parkin, and -synuclein proteostasis
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Poster Session 1: 153 Do KQ, Trabesinger AH, Kirsten-Krger M, Lauer CJ, Dydak U, Hell D, Holsboer F, Boesiger P, Cunod M (2000) Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo
A second family, BPC-157 and TB-500, targets tissue repair rather than the GH axis: BPC-157 is proposed to work through angiogenesis, nitric-oxide signaling, and anti-inflammatory activity, while TB-500 binds actin to promote cell migration, blood-vessel formation, and collagen deposition