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The role of NAC in glutamate homeostasis has prompted research into the use of NAC for the treatment of addiction

The oral-gut axis thus serves as a critical mediator in systemic inflammation and disease progression, with specific microbial taxa offering potential biomarkers for early detection, as seen in oral cancer where Haemophilus parainfluenzae and Rothia mucilaginosa are malignancy-associated (Nayyar et al., 2025)

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Zafardoust et al., 2023b)