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Curiously, while the expression of key polyamine synthetic enzymes are primarily neuronal in the brain, the bulk of Spd and Spm in the brain is stored in astrocytes, with the notable exception of specific neuronal sub-populations such as neurosecretory cells (Laube and Veh, 1997

10.1186/s13075-022-02979-4 13 BreitsamerM.WinterG

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found that MET is also expressed in a subgroup of the encephalogenic CD8 + cell population, which is significantly increased at the peak phase of clinical disease in EAE immunized mice and decreased at the recovery stage