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Currently used diagnostic biomarker methods, such as cerebrospinal fluid (CSF) analysis and positron emission tomography (PET) imaging, provide valuable information but are invasive, expensive and not suitable as a front-line screener 5,7

Optimization strategies in modern extraction workflows focus on critical variables such as solvent composition, sample pH, ionic strength, and temperature control

instead, research points to interactions with the nitric oxide (NO) system, growth factor receptor upregulation, and modulation of several cytokine pathways

Because of this, many people previously turned to expensive and invasive intravenous (IV) treatments