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& Magoffin, D

Together, ferroptosis and melanocyte loss are characterized by mitochondrial malformations, glutathione peroxidase inactivation, p53 elevation, ROS accumulation, and lipid peroxidation (98, 99)

10 SIDE EFFECTS ASSOCIATED WITH HYDROQUINONE Mild erythema Burning sensation Dryness Fissuring of paranasal and infraorbital areas Stinging Localized hypersensitivity Pruritus Scaling Exogenous ochronosis HYDROQUINONE WARNINGS Contains sodium metabisulfite which may cause an allergic-type reaction including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in susceptible people

It recommends that glutathione infusions be reserved for specific medical conditions and conducted under close supervision