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10.1093/jn/131.2.568S 233

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Animal experiments have demonstrated that high-fat diet downregulates tight junction protein expression (such as occludin and ZO-1), reduces mucus layer thickness, and increases intestinal permeability (89)

Harvard declined to release Sinclairs conflict-of-interest statements, which university policy requires faculty at the medical school to file in order to protect against any faculty bias that could heighten the risk of harm to human research participants or recipients of products resulting from such research. We can only be proud of our collaborations if we can represent confidently that such relationships enhance, and do not detract from, the appropriateness and reliability of our work, the policy states