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An ischaemic lesion was detected in NECT at admission in 5 patients (25%) and an arterial occlusion was detected in 15 patients (75%) in CTA

In the 1970s, clinical trials on patients with terminal cancer showed that intravenous high-dose ascorbate treatment, that achieved a peak plasma concentration of 6 mM, extended their survival (143, 144), whereas in the 1980s they failed to confirm these findings because ascorbate was given at the same dose orally and the peak plasma concentration was of less than 200 M (145, 146)

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