This is particularly important if you are part of any of the groups considered to be at high risk of B12 deficiency, including alcoholics, smokers, those on diabetes drugs, adults over 65, those with gastrointestinal disorders and those who have had surgery relating to the digestive tract
Earlier oral trial METAOD005 randomized 300 adults with obesity to oral AOD-9604 (1, 5, 10, 20, or 30 mg/day) or placebo for 12 weeks
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Physical changes like pale skin or a sore tongue, and digestive issues such as loss of appetite or constipation, may also be signs your body needs more B12