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10.1016/j.chom.2017.11.004 166

Safety Considerations and Contraindications GHK-Cu is generally well-tolerated in topical form, but caution is warranted in patients with certain sensitivities or systemic conditions

Yes, but precision depends on dose size

In fact, the FDA in the Philippines warns that using injectable glutathione for skin lightening may be risky, as it could harm the kidneys, liver, and nervous system