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DNA Repair: NAD+ helps repair damaged DNA and keeps your cells functioning well

There are several B12 supplements available, and some (like B12 tablets) have high dosages far above the daily recommended value

In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis

Supplemental material Intervention and placebo The active substance of vitamin B 12 given in the study is 2 mL mecobalamin (5 mg/ml), administered intramuscularly.25 Placebo substance is 2 mL sodium chloride (9 mg/ml), isotonic solution for parenteral use (Baxter) intramuscularly.26 All participants are informed that their urine may turn red, which may occur during mecobalamin injections