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Cell 169 , 132147.e16 (2017)
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Storage and stability Before reconstitution: Freezer (-20C): 12-24+ months Refrigerator (2-8C): 6-12 months Room temperature: Not recommended (days only) After reconstitution: Refrigerator (2-8C): 28-30 days maximum Never freeze liquid peptide Protect from light (amber vial or box) Maintain sterile technique always Visual quality check: Should be clear, slightly blue-tinted No particles or cloudiness If contaminated (cloudy, particles) discard See our peptide storage guide , how long reconstituted peptides last in fridge , bacteriostatic water for peptides , water to mix with peptides , and lyophilized vs liquid peptides
