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Treatment Group: Subjects will be assigned to a single treatment group receiving TB-500 nasal spray

The nasal mucosa is highly vascularized, allowing absorption directly into circulation, and some evidence suggests nasal administration may provide more direct central nervous system access via the olfactory pathway

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Published in vitro and animal-model research has examined NNMT inhibition in connection with several areas of scientific interest, including adipocyte metabolism, NAD pathway regulation, mitochondrial function, and cellular energy signaling