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Lentiviral vectors (LV), adeno-associated virus (AAV), and lipid nanoparticles (LNP) are among the most studied delivery systems for intra-articular applications

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In addition, second-line treatments such as GnRH agonists effectively reduce pain but are compromised by significant menopausal side effects and challenges with long-term tolerability, which has prompted the development of novel oral GnRH antagonists like elagolix, linzagolix, and relugolix that offer dose-dependent estrogen suppression and rapid reversibility

The cosmetic outcome of sutured wounds is improved if they are covered with an occlusive dressing for at least four days