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Given that GSH levels in the brain may also vary due to polymorphisms in GSH-associated genes (e.g., different Gclc polymorphisms (Xin et al., 2016)), we recommend that future studies also take genotype into consideration

Research indicates that higher glutathione levels are associated with better cellular function and longevity

[Related: See our full Peptide Therapy Series] Rudy Commentary Epithalon is one of the more intriguing peptides in longevity medicine because it targets telomere biology, a mechanism closely tied to cellular aging

Most critically, while the mechanistic and preclinical foundation is strong, clinical studies in humans would be required to establish optimal dosing, administration schedules, safety profiles, and actual synergistic effects for this specific combination