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16 Most studies included patients with various aetiologies of B12 deficiency, including pernicious anaemia, and improvements were seen across different causes

Similarly, during the finishing period on feedlot, increasing levels of RPM, along with 4 g/head/day of supplemental lysine, did not affect animal performance (BW, ADG, DMI) ( It is important to emphasize that the inefficient utilization of high-protein diets in the rumen can result in excessive nitrogen losses to the environment, thereby contributing to the production of environmentally harmful gases ( In terms of maternal performance, gestating beef cows appear not to respond to RPM supplementation, as no effects have been observed on BW or body condition score (BCS)

It is not available as a licensed medicine through the NHS, and it is not listed in the British National Formulary (BNF)

For treatment, extensive topical broad-spectrum antibiotic can be started in addition to glaucoma drug and pupil dilatation [42]