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The concern stems from its activation of the VEGFR2 pathway and FAK-paxillin signaling, which drive angiogenesis and are dysregulated in 50% of human cancers (ovarian cancer, melanoma, and colon adenocarcinoma)

Statistical analysis Statistical significance between two groups was determined with a Student t test, and statistical significance among multiple groups was determined with one-way analysis of variance, followed by a Tukey post hoc test using GraphPad Prism software version 8 (GraphPad Software Inc., San Diego, CA)

May 24 2017;57(8):1749-1758

Identification of an anti-inflammatory potential of Eriodictyon angustifolium compounds in human gingival fibroblasts