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Although the terms direct and indirect are used equivalently with conjugated and unconjugated bilirubin, this is not quantitatively correct, because the direct fraction includes both conjugated bilirubin and delta bilirubin

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Yuan Y, Tong Q, Zhang L, et al

Notably, a recent study carried out in a diabetic population has reported positive effects of treatment on corneal nerve fiber density (although over a longer time scale, with no change in the skin biopsy nerve density of the distal extremity) (33)