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The IGF-1 signaling axis is widely studied for its involvement in cellular proliferation, metabolic regulation, tissue growth, and intracellular signaling mechanisms in preclinical research models

Vitamin D metabolism Vitamin D receptor (VDR) plays a critical role in vitamin D metabolism [104]

However, one challenging issue is to retain the biological activities (e.g., antioxidant, anti-microbial, and anti-inflammatory) and functional properties (e.g., emulsifying capacity, water holding capacity, and foaming stability) of PPDP during the extraction and the following processing stages, thus maintaining their health-promoting benefits

The direct comparison upon using the same concentration of ruthenium of the molecular agent Ru(II)-OH and NP4 showed a significantly higher tumor accumulation of the nanoparticle formulation NP4 (Supplementary Fig