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These substances have been or will be reviewed by the Pharmacy Compounding Advisory Committee, which will make recommendations to the FDA as to whether these items should be on the positive list

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While this has some inherent logic, it has not been fully explored whether it is valid to assume a linearity of the relationship between gene and serum UA in which genetic polymorphisms differentiating normal and high UA associated with, say, risk of gout are the same as those differentiating normal and low UA associated with risk of PD