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Abnormal iron metabolism is a significant trigger for ferroptosis, with iron-related proteins including transferrin receptor protein 1 (TfR1), ferritin (FTH and FTL), and iron export proteins playing essential roles in iron homeostasis

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Indeed, ferroptosis occurs through the intersection of multiple pathways to form an intricate regulatory network with obesity, so that one or more cells in the AT ferroptosis has the potential to change the fate of the entire tissue development