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Chronic treatment with DXT increases the expression of connexin 43 (Cx43), a crucial component of astrocyte gap junctions, in the rat PFC, preventing chronic unpredictable stress-induced dysfunction of astrocyte gap junctions and reversing the depressive-like behaviors caused by gap junction inhibition

The cytotoxicity of vitamin C can be explained by vitamin C-mediated increase in the levels of hydrogen peroxide and the formation of hydroxyl radicals via the Fe-Fenton reaction

Kalodiki E, Fareed J, Syed D, Geroulakos G, Hoppensteadt D, Lattimer CR

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