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As a physician, youre aware that compounds like BPC-157 currently lack robust human clinical trials, and long-term safety, dosing standards, and management of potential adverse effects are still unclear

Zlokovic BV, Susic VT, Davson H, Begley DJ, Jankov RM, Mitrovic DM, Lipovac MN

2006 Mar-Apr;20(2):253-7

In a related rat model, activation of p62/Nrf2 and downregulation of ROS were also observed, as evidenced by reductions in arthritis scores and pathological features (marked infiltration of inflammatory cells, synovial hyperplasia, cartilage damage and bone destruction), as well as inhibition of NFATc1 and other osteoclast activities and bone resorption regulators (CTSK and MMP-9)