Indeed, the inhibition of GT or cysteine S -conjugate -lyase (both highly expressed in proximal tubule cells of the kidney) blocks the nephrotoxicity of cisplatin in mice (Townsend et al., 2003)
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In women with mild tubal disease affecting the portion of the tube closest to the ovary, surgery to open the tube can improve fertility, although it also increases the risk of ectopic (tubal) pregnancy
Martinez-Jothar L, Doulkeridou S, Schiffelers RM, Sastre TJ, Oliveira S, van Nostrum CF, Hennink WE