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IV infusion (clinic-based) Protocol: Continuous daily supplementation -- typically 250-1000 mg NMN or 300-600 mg NR per day Rationale: NAD+ depletion is continuous, requiring ongoing replenishment to maintain elevated levels Requirements: No special handling for oral supplements

10.1186/s13075-018-1592-1 8 Batini-HaberleI.RebouasJ

Additional literature suggests that peptide-mediated regulation of cytokines and chemokines shapes the directional movement of immune populations toward injured sites, enabling coordinated repair rather than uncontrolled inflammation

Research has shown that supplementation with selenium in persons who are deficient in selenium and suffer from autoimmune thyroiditis may lower levels of thyroid autoantibodies and improve clinical results [51]