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(A) shows the association of rs713041 genotype (GPX4) with pre-diagnosis erythrocyte GPx (eGPx) activity (Anova, p = 0.015)

These cells, also known as senescent or zombie cells, seem to be stuck between life and death

When the gr overexpression strain was compared with the control strain (wild type carrying plasmid pJRD215), the expression levels of glutathione reductase and heterodisulfide reductase subunit C were increased after incubation for 1 and 2 h, respectively, while the expression levels of thioredoxin-disulfide reductase and sulfur dioxygenase were decreased after incubation for 1 h, and the expression levels of peroxiredoxin were decreased after incubation for 2 h, respectively