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Increased blood concentration of homocysteine is another nonspecific biomarker of vitamin B 12 deficiency that has been linked to depressive symptoms in the elderly (108)
Vitamin B12 is a water-soluble vitamin that your body uses for a variety of processes, including producing energy and maintaining a healthy brain and nervous system
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Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet
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