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The large open reservoirs and hanging-drop openings, combined with continuous recirculation of the medium, prevent the formation of potentially hypoxic regions in the small microchannels, an issue that may occur in plastic platforms but is rarely experienced with PDMS-based systems 54

Zapata-Prez R, Tammaro A, Schomakers BV, Scantlebery AML, Denis S, Elfrink HL, et al

While the exact causes of ADHD are not fully understood, the disorder is commonly treated with psychostimulants [35,36], such as methylphenidate (MPH), dexmethylphenidate, dextroamphetamine, mixed amphetamine salts, pemoline, and modafinil [35]

However, the affinity of MR for its ligands is 10 times higher than that of GR for its ligands