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Simultaneously, an increase in Ptgs2 (a marker gene for ferroptosis) gene expression was observed in the livers of mice in the iron overload group, which was significantly reduced by the intervention of theaflavins (Fig

Accordingly, rather than downplaying the crucial role of ADE in dengue pathogenesis, the two-hit hypothesis offers a complementary perspective that, alongside ADE, may help clarify some of the unresolved questions about disease progression

The levels of serum IL-8, TNF-, SOD3, and GPX1 were assessed before therapy, as well as at one and two months after treatment, in both cohorts

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