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Following ovulation, the corpus luteum secretes estradiol, progesterone and inhibin A, and the age-related decline in luteal function may also affect the quality of the secretory endometrium (Tarnawski et al., 2007) and endothelial cells obtained from the gastrointestinal tract of aging rats demonstrate decreased angiogenesis ( Aging of endometrial stem cells, and/or harnessing endometrial stem cells as potential therapeutics for the aging endometrium, are other potential areas of research

The hallmark is morning stiffness lasting more than 30 minutes that improves with movement rather than rest

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& Whittaker, G