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It was found that 48-h exposure to rotenone significantly increased Ca 2+ content, indicated by Fluo3(i) fluorescence, and increased ceramide content, decreased cell size measured as FSC, and increased annexin V binding

The Phase II detoxification pathway, in which glutathione plays the central role, represents the critical step that converts potentially harmful substances into water-soluble compounds suitable for elimination

Similar to shGDH1 cells, antioxidants (NAC and catalase) failed to restore either cytosolic NADPH levels (Extended Data Fig

You'll likely see steady improvement over a few months as you stick with healthier habits