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With further research, it is expected to transform from a research tool into a clinical drug, filling the niche in targeted metabolic therapy, especially in the combined intervention of obesity and type 2 diabetes, where it holds unique application potential

To avoid hypertension as a potential confounding factor, we decided to test the SHR rats and WKY rats at 4 weeks old, and therefore they were a lot smaller compared to the SD rats in the previous experiment

Despite these strengths, it is important to address several methodological limitations

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