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(2013) The landmark microneedling study showed that microneedling alone activates many of the same wound-healing pathways (Wnt/-catenin, VEGF) that GHK-Cu targets through gene expression modulation suggesting a powerful synergy when combined

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Photodegradation can be also induced by impurities (e.g., iron compounds in citrate buffers) (Baertschi et al