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It helps reduce inflammation and supports skin healing

Experimental results demonstrated that apelin-13, an endogenous ligand of the G protein-coupled receptor angiotensin II protein J (APJ), increased DRP1 expression, inhibited fusion-related protein expression, and stimulated VSMC mitophagy and abnormal proliferation, which exacerbated the development of atherosclerosis [227]

Pro-Brain-Derived neurotrophic factor (BDNF), but not mature BDNF, is expressed in human skeletal muscle: implications for Exercise-Induced neuroplasticity

New functional neurons generated in this region contribute to learning and mood regulation, and thus represent a unique form of neural plasticity