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Inhibition of induced-MNU mammary carcinogenesis by molecular iodine (I 2 ) but not by iodide (I ) treatment: evidence that I 2 prevents cancer promotion

This is important because TNF-alpha is a driver of inflammation in IBD and a target of current therapeutics like infliximab (Remicade/Inflectra) and adalimumab (Humira)

Studies report downregulation of Bax, cytochrome c, cleaved caspase-3, and upregulation of Bcl-2 levels upon quercetin administration in rodent models