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Although evidence has shown the presence of XO in the human brain, which catalyzes purine metabolism to UA, the concentration of UA generated in situ in the brain is low

For laboratories investigating the downstream growth factor signalling pathway separately, our IGF-1 LR3 research guide provides detailed information on how IGF-1 LR3 is used to study growth factor receptor biology in controlled research settings

These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303