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We speculate that endogenous GABA degraded to promote synthesis of other stress response substances and feedback to the TCA cycle at low temperature, which showed that other amino acid contents and the DAPs in the TCA cycle were up-regulated at low compared to optimum temperature

Intestinal dysbiosis is related to the disruption of hippocampal serotonergic system regulation and the induction of mood and anxiety disorders in animal models (199)

Mitochondrial peptides like MOTS-c and cellular reset peptides like Epithalon operate through different mechanisms that are not subject to the same concern

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