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Several nutrients and microbial metabolites, such as B complex vitamins, SCFAs, and polyphenols, have epigenetic potential and can influence fetal programming during sensitive developmental periods

This finding supports the idea that the mutation in pad2-1 close to the glutamate conjugating residues of GSH1 might influence the affinity of the enzyme for BSO, as it was proposed for cad2-1 54,71

Moreover, their antifungal spectrum is narrow, making it difficult to address mixed infections or fungal morphological transitions (Wang et al., 2022

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