IGF-1 LR3 Synonyms / Designations: IGF-1 LR3, Long Arg IGF-1, Insulin-Like Growth Factor-1 LR3, Recombinant IGF-1 analogue CAS Number: 946870-92-4 Molecular Formula: C400H625N111O115S9 Molecular Weight: 9117.5 g/mol Peptide Classification: Synthetic analogue of insulin-like growth factor-1 (IGF-1) Purity: 99 % (HPLC, typical) Appearance: White to off-white lyophilised powder Pack Size: 1 mg (total) Storage: Desiccated, protected from light, stored at 20 C Solubility: Soluble in sterile water and buffered aqueous solutions Description & Mechanism IGF-1 LR3 is a synthetic analogue of human insulin-like growth factor-1 (IGF-1) incorporating an arginine substitution at position 3 and an extended N-terminal sequence
Epigenetically mediated GSTP1 silencing is associated with enhanced cancer susceptibility by decreasing its caretaker gene function, which tends to promote neoplastic transformation allowing cells to acquire additional alterations
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