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After the specified room temperature storage period expires, the medication should be discarded even if doses remain, as potency cannot be guaranteed beyond these timeframes

Long Half-Life: In rat studies, Dihexa's terminal half-life is as long as 12.68 days (intravenous injection) and 8.83 days (intraperitoneal injection)

Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines

Eosinophils at the beginning of the trajectory expressed immediate early response genes ( Fos , Fosb , Junb ) and Cd24a , reflecting recent activation (Shaulian and Karin, 2002) and blood origin (Gurtner et al, 2023) (Fig