Barnes LL, Dhana K, Liu X, et al
Intranasal Use Only: Designed exclusively for intranasal administration, each spray of COBANERVE-B12 delivers 250 mcg of Methylcobalamin, ensuring targeted and effective supplementation
Drug Interactions 7.1 Other Drugs that may Increase Risk of Hyponatremia The concomitant administration of DDAVP Nasal Spray with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, NSAIDs, lamotrigine, oxybutynin and carbamazepine) requires more frequent serum sodium monitoring [see Warnings and Precautions (5.1) and Adverse Reactions (6)]
The only rule is to label each vial clearly and update your dosing calculations for the new concentration