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The eligibility criteria for most FDA-approved weight loss drugs are as follows: Body mass index (BMI) of 30 or higher (classified as obesity) Body mass index (BMI) of 27 or higher (classified as overweight) with one weight-related health condition, such as hypertension, hyperlipidemia, heart disease, and high blood cholesterol levels

Methods Experimental model and details Animal studies All animal studies were performed according to protocols approved by the University Committee on Animal Resources at the University of Rochester Medical Center

The 2020 Xu et al

While not every user becomes deficient, the risk is substantial enough to warrant proactive supplementation, particularly during aggressive weight loss phases