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PE-22-28 Evidence# PE-22-28's evidence comes primarily from French research groups associated with its development: TREK-1 pharmacology

They added that a peptide called TB-4, and a similar synthetic peptide, TB-500, showed some signs of promoting blood vessel formation and tissue repair in cell studies and animal research, but the experts noted that human data around musculoskeletal conditions are lacking

Another study is testing how CagriSema works over longer periods and in people with higher body weights, with results expected around the first half of 2027

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