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HCA of plasma metabolites significantly affected by HbA and HbS levels in SS patients identified a significant increase in the levels of free fatty acids (palmitoleic, myristoleic, myristic, stearic, docosapentaenoic, arachidonic, dihomogammalinolenic and adrenic acid) as a function of high levels of HbA, as opposed to declines in a series of acyl-carnitines (5:0, 5:0 OH, 14:0, 16:1

Comparing the decreasing number of recoverable bacteria by PFU assay (Fig

This enabled us to assess whether the structural differences and conformational dynamics observed in the Cagri and rAmy bound AMYR structures alter the nature of Gs protein interaction (Supplementary Fig

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