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In APP/PS1 (Amyloid Precursor Protein/Presenilin 1) transgenic mice, a well-characterized transgenic model of AD, HTyr treatment improves performance in the Morris water maze test, reduces cortical and hippocampal apoptosis, and restores synaptic integrity (42)

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Selenium content of the soil varies worldwide, depending on the pH of the soil, organic matter, soil composition, agricultural activity, and mining.[ref] Here is the variation in selenium across US states (USGS map): Plants are the primary source of selenium in foods for humans and animals

So, alcohol both increases the toxic compound and decreases the detoxifying material