Difficulties in replicating findings is unfortunately the case of many MRS studies, in both ME/CFS and other conditions
Furthermore, a 28-day feeding study of SD rats showed that L-theanine could increase the content of total short-chain fatty acids and regulate intestinal mucosal immunity based on dietary fiber feeding (95)
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Conversely, the placebo group only achieved a 3.6% weight reduction, primarily from a greater loss of lean mass [36, 37]